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Marina Guenza

Marina Guenza profile picture
  • Title: Professor
  • Additional Title: Theoretical Physical Chemistry - Structure and Dynamics of Complex Fluids - Novel Computational Methods
  • Phone: 541-346-2877
  • Office: 136 Klamath Hall
  • Affiliated Departments: Institute of Molecular Biology, Institute Theoretical Science, Materials Science Institute
  • Website: Website


M.S., University of Genoa, Italy, 1985 (Angelo Perico). Ph.D., Consortium of the Universities of Genoa, Turin, and Pavia, Italy, 1989. 1989–99 Tenured Researcher, National Council of Research, Italy. 1994 Visiting Scientist at University of Chicago, James Franck Institute, with Karl F. Freed. 1995–97 Visiting Scientist at University of Illinois at Urbana-Champaign,  with Ken S. Schweizer. 1998-1999 Visiting Scientist, University of Oregon. 2002-2006 Assistant Professor, University of Oregon. 2006-2012 Associate Professor, University of Oregon. 2012 - present, Professor, University of Oregon.

Honors and Awards:
2015 University of Oregon Interdisciplinary Research Award
2015 University of Oregon Faculty Excellence Award
2011 - present, Fellow of the American Physical Society
2010-2013 Editorial Advisory Board of Macromolecules
1985-1988, Italian Ministry of Public Instruction fellow
Memberships: American Chemical Society, American Physical Society, Biophysical Society, American Association for the Advancement of Science


The Guenza group studies the structure and dynamics of complex macromolecular fluids using equilibrium and non-equilibrium statistical mechanics. For more details see our webpage.


Research Gate Profile

Recent Publications:

M. G. Guenza, M. Dinpajooh, J. McCarty, I. Y. Lyubimov “Accuracy, Transferability, and Efficiency of Coarse-Grained Models of Molecular Liquids” The Journal of Physical Chemistry B (2018) in print. DOI: 10.1021/acs.jpcb.8b06687. Publication Selected as Editor’s Pick and Feature Article.

M. Dinpajooh, M. G. Guenza “Coarse-graining simulation approaches for polymer melts: the effect of potential range on computational efficiency” Soft Matter, 14, 7126-7144 (2018). Cover paper.

M. Dinpajooh, M. G. Guenza “On the Density Dependence of the Integral Equation Coarse-Graining Effective Potential” The Journal of Physical Chemistry B, 122(13), 3426-3440 (2018). DOI: 10.1021/acs.jpcb.7b10494. 

M. Dinpajooh, and M. G. Guenza “On the Density Dependence of the Integral Equation Coarse-Graining Effective Potential" The Journal of Physical Chemistry B (2017) DOI:10.1021/acs.jpcb.7b10494.

P. G. Romano and M. G. Guenza “GRadient Adaptive Decomposition (GRAD) Method: Optimized Refinement Along Macrostate Borders in Markov State Models" The Journal of Chemical Infromation and Modeling 57, 2729-2740 (2017). 

J. Copperman, M. Dinpajooh, E. Beyerle, and M. G. Guenza “Universality and specificity in protein fluctuation dynamics" Physical Review Letters, 119, 158101 (2017).

M. Dinpajooh, and M. G. Guenza “Thermodynamic Consistency in the Structure-based Integral Equation Coarse-Grained Method" Polymers, 117, 282-286 (2017).

E. deLorimier, M. N. Hinman, J. Copperman, K. Datta, M. Guenza, and J. A. Berglund “Pseudouridine Modification Inhibits Muscleblind-like 1(MBNL1) Binding to CCUG Repeats and Minimally Structured RNA through Reduced RNA Flexibility” Journal of Biological Chemistry, 292, 4350-4357 (2017).

J. Copperman and M. G. Guenza “Mode localization in the cooperative dynamics of protein recognition" The Journal of Chemical Physics 145, 0151011-12 (2016).

D. Ozog, A. D. Malony, M. G. Guenza "The UA <-> CG Workflow: High Performance Molecular Dynamics of Coarse-Grained Polymers" 24th Euromicro International Conference on parallel, Distributed and Network-Based Processing - DPD'2016.

J. Copperman and M. G. Guenza “Predicting protein dynamics from structural ensembles” Journal of Chemical Physics, Invited Contribution for Special Topics Issue on Coarse Graining of Macromolecules, Biopolymers, and Membranes” 143, 243131-12 (2015).

A. J. Clark, J. McCarty, and M. G. Guenza “Comment on Systematic and simulation-free coarse graining of homopolymer melts: A structure-based study” Journal of Chemical Physics 143, 067101 (2015).

M. G. Guenza “Advancements in multi scale modeling: Adaptive resolution simulations and related issues” European Physics Journal Special Topics (EPJ-ST) in "Scale Bridging Techniques in Molecular Simulation: A critical Appraisal" L. Delle Site and C. Hartmann Ed., 224, 2491-2495 (2015). 

M. G. Guenza "Thermodynamic consistency and other challenges in coarse-graining models" European Physics Journal Special Topics (EPJ-ST) in "Scale Bridging Techniques in Molecular Simulation: A critical Appraisal" L. Delle Site and C. Hartmann Ed., 224, 2177-2191 (2015). 

D. Ozog, J. McCarty, G. Grossett, A. D. Malony, M. G. Guenza “Fast equilibration of coarse-grained polymeric liquids” Journal of Computational Science 9, 33 (2015).

M. G. Guenza "Structural and thermodynamic consistency in coarse-grained models of macromolecules”  Journal of Physics: Conference Series 640,  0120091 (2015)

M. G. Guenza "Thermodynamically Consistent Coarse-Graining of Polymers" in "Coarse-Grained Modeling of Biomolecules" (Series in Computational Biophysics by Tylor & Francis Publisher, G. Papoian Ed. 2017) arXiv:1509.08546.

J. Copperman, M. G. Guenza “A Coarse-Grained Langevin Equation for Protein Dynamics: Global anisotropy and a mode approach to local complexity” 119, 9195-9211 (2015) Journal of Physical Chemistry B, Festschrift issue honoring Branka Ladanyi.

E. de Lorimier, L. Coonrod, J. Copperman, A. Taber, E. Reister, K. Sharma, P. K. Todd, M. Guenza, J. A. Berglund “Modifications to toxic CUG RNAs induce structural stability and rescue missplicing in Myotonic Dystrophy” Nucleic Acid Research 42, 12768 (2014).

J. McCarty, A. Clark, J. Copperman, and M. G. Guenza “An analytical coarse-graining method which preserves the free energy, structural correlations, and thermodynamic state of polymer melts from the atomistic to the mesoscale” J. Chem. Phys. 140, 204913 (2014).

 M. G. Guenza “Localization of Chain Dynamics in Entangled Polymer Melts” Phys. Rev. E 89, 052603 (2014).