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Undergraduate Chemistry and Biochemistry Courses

111 Introduction to Chemical Principles (4) Chemical concepts for students in health care, biological applications, and environmental studies. Topics include atomic structure, solutions, acids, bases, stoichiometry, equilibrium, biomolecules, and organic functional groups. Lecture, demonstration. Prereq: MATH 95.

113 The Chemistry of Sustainability (4) Illustrates how chemistry provides innovative materials, processes, and consumer products that support sustainable solutions to problems of energy utilization, global warming, and pollution prevention. Prereq: MATH 95; high school chemistry.

114 Green Product Design (4) Illustrates how green chemistry, product design, advertising, and sustainable business practices are used to design greener consumer products and accelerate their adoption in the market. Prereq: MATH 95 or higher.

221, 222, 223 General Chemistry (4,4,4) First-year university chemistry: atomic and molecular structure, thermodynamics, equilibrium, physical properties, and the chemical reactions of the elements. Lectures. Prereq for 221: high school chemistry; pre- or coreq: MATH 111. Concurrent CH 227 or 237 recommended. Prereq for 222: CH 221 or 224H; pre- or coreq: MATH 112. Concurrent CH 228 or 238 recommended. Prereq for 223: CH 222 or 225H. Concurrent CH 229 or 239 recommended. Students cannot receive credit for both CH 221-223 and 224-226H.

227, 228, 229 General Chemistry Laboratory (2,2,2) Teaches laboratory skills through chemical reactions and writing equations, phase diagrams, equilibrium constants, acid-base titrations, volumetric analyses, voltaic cells, exercises inkinetics and inorganic chemistry. Pre- or coreq for 227: CH 221 or 224H; MATH 111. Prereq for 228: CH 227 or 237; pre- or coreq: CH 222 or 225H; MATH 112. Prereq for 229: CH 228 or 238; pre- or coreq: CH 223 or 226H.

224, 225, 226 (H) Honors General Chemistry (4,4,4) First-year university chemistry for students with excellent backgrounds in high school chemistry, physics, and mathematics. Chemical structure, equilibrium dynamics, thermodynamics, reactions, and an introduction to quantum chemistry. Prereq for 224H: high school chemistry; MATH 112 or equivalent; pre- or coreq: MATH 241 or 251 or 261. Concurrent CH 237 recommended. Prereq for 225H: CH 221 or 224H; pre- or coreq: MATH 242 or 252 or 262. Concurrent CH 238 recommended. Prereq for 226H: CH 222 or 225H; pre- or coreq: MATH 243 or 253 or 263. Concurrent CH 239 recommended. Limited to selected students; primarily for prospective chemistry and other science majors and for Clark Honors College students. Students cannot receive credit for both CH 221-223 and 224-226H.

237 Advanced General Chemistry Laboratory (2) Experiments in chemistry emphasize gravimetric techniques, periodic relationships, chemical equations, phase diagrams, volumetric and spectrophotometric techniques. Prereq: MATH 112; Pre- or coreq: CH 221 or 224H.

238, 239 Advanced General Chemistry Laboratory (2,2) Experiments in chemistry use spectrophotometric, titrimetric, and electrochemical techniques and culminate in a laboratory research project. Prereq for 238: CH 227 or 237; pre- or coreq: CH 222 or 225H. Prereq for 239: CH 228 or 238; pre- or coreq: CH 223 or 226H.

331 Organic Chemistry I (4) Structure, properties, and bonding of organic molecules. Prereq: CH 223 or 226H. Concurrent CH 337 recommended.

335 Organic Chemistry II (4) Reactions and mechanisms of organic chemistry. Prereq: CH 331. Concurrent CH 338 recommended.

336 Organic Chemistry III (4) Organic chemistry of biomolecules with a focus on chemical aspects. Prereq: CH 335. Concurrent CH 339 recommended.

337, 338 Organic Chemistry Laboratory (3,3) Principles and techniques of laboratory practice in organic chemistry. Prereq for 337: CH 229 or 239; pre- or coreq: CH 331. Prereq for 338: CH 337; pre- or coreq: CH 332 or 335.

339 Organic Analysis (4) Qualitative analysis and structure determination of unknowns. Prereq: CH 337, 338 with grades of C- or better; pre- or coreq: CH 336 or equivalent.

341 Majors Track Organic Chemistry I (4) Structure, properties, and bonding of organic molecules. Provides a rigorous foundation appropriate for chemistry and biochemistry majors as they become chemical practitioners. Sequence with CH 342, 343. Prereq: CH 223 or CH 226H. Concurrent CH 337 recommended.

342 Majors Track Organic Chemistry II (4) Focuses on mechanisms and reactions of common organic functional groups. Sequence with CH 341, 343. Prereq: CH 331 (with grade of B– or better) or CH 341. Concurrent CH 338 recommended.

343 Majors Track Organic Chemistry III (4) Incorporates topics from the recent chemistry literature. Sequence with CH 341, 342. Prereq: CH 335 (with grade of B– or better) or CH 342. Concurrent CH 339 recommended.

CH 348 Organic Chemistry Lab for Majors (4) [Graded only for majors] Problem solving in the organic chemistry laboratory. Sequence with CH 337, 349. Prereq: CH 337; coreq CH 342.

CH 349 Organic Chemistry Lab for Majors (4) [Graded only for majors] Organic chemistry laboratory projects. Two-dimensional nuclear magnetic resonance techniques. Sequence with CH 337, 348. Prereq: CH 348; coreq: CH 343.

360 Physiological Biochemistry (4) For preprofessional health science students. Topics include protein structure and function, enzyme mechanisms, central metabolism and bioenergetics, integration and regulation of metabolism by hormone action. Prereq: CH 336 or 343; BI 214 or 282H recommended. Students cannot receive credit for both CH 360 and 462.

401 Research: [Topic] (1-21R) Introduction to methods of chemical investigation. For advanced undergraduates by arrangement with individual faculty members.

403 Thesis (1-12R) Open to students eligible to work for a bachelor’s degree with honors in chemistry or biochemistry.

409 Special Laboratory Problems (1-21R) Nonresearch-oriented laboratory instruction and off-campus research and laboratory experience.

410 Experimental Course: [Topic] (1-5R)

411, 412, 413 Physical Chemistry (4,4,4) Methods of physics applied to chemical problems, including inorganic, organic, and biochemistry. Introduction to chemical thermodynamics, rate processes, and quantum chemistry. Prereq: two years of college chemistry (except for physics majors), PHYS 201, 202, 203; MATH 253. MATH 256, 281, 282 strongly recommended.

417, 418, 419 Physical Chemistry Laboratory (4,4,4) Experiments in thermodynamics, chemical kinetics, and molecular spectroscopy to illustrate theoretical principles. Pre- or coreq for 417: CH 411; Pre- or coreq for 418: CH 412; Pre- or coreq for 419: CH 413.

CH 420 Physical Organic Chemistry I (4) [Graded only for majors] Modern physical organic chemistry including chemical bonding, acid-base chemistry, thermochemistry, noncovalent interactions, and introduction to computational chemistry. Sequence with CH 421/521. Prereq: CH 336.

CH 421 Physical Organic Chemistry II (4) Modern physical organic chemistry including tools to study reaction mechanisms, kinetic analysis, isotope effects, and qualitative molecular orbital theory. Sequence with CH 420/520 Prereq: CH 420/520.

429 Instrumental Analysis (5) Use of instrumental methods for quantitative determinations of unknown chemical samples. Prereq: CH 417.

431, 432, 433 Inorganic Chemistry (4,4,4) 431/531: introduction to group theory for molecular symmetry; syntheses, structures, reactions, and reaction mechanisms of coordination complexes and organometallic complexes.

432: Bioinorganic Chemistry: metals in biological systems; coordination chemistry, reactions, spectroscopy, metalloclusters, and synthetic modeling.

433: solid-state inorganic chemistry: solid-state structure and its determination; the electrical, magnetic, and mechanical properties of materials and their physical description. Prereq: CH 413/513.

441 Quantum Chemistry (4) The principles of time-independent quantum mechanics and their application to model atomic and molecular systems. Prereq: CH 413/513 or equivalent.

442, 443 Quantum Chemistry and Spectroscopy (4,4) 442/542: molecular structure theory, perturbation theory, time-dependent quantum mechanics, theory of spectra, selection rules. 443/543: experimental spectra of atomic and molecular systems and surfaces. Prereq: CH 441/541 or equivalent.

444 Chemical Thermodynamics (4) The laws of thermodynamics and their applications, including those to nonideal chemical systems. Prereq: CH 413/513 or equivalent.

445 Statistical Mechanics (4) Molecular basis of thermodynamics. Applications to the calculations of the properties of noninteracting and weakly interacting systems. Prereq: CH 413/513 or equivalent.

446 Chemical Kinetics: [Topic] (4R) Description and interpretation of the time evolution of chemical systems. Prereq: CH 413/513 or equivalent.

CH 447 Computational Chemistry (4) Introduction to modern computational methods used to understand the properties of molecules. Prereq: CH 411, 412; or PHYS 353.

451 Advanced Organic-Inorganic Chemistry (4) Principles of organic-inorganic reaction dynamics; kinetics and mechanisms, linear free-energy relationships, isotope effects, substitution reactions, dynamic behavior of reactive intermediates, electron transfer chemistry. Prereq: CH 336 or equivalent.

452 Advanced Organic Chemistry-Stereochemistry and Reactions (4) Principles and applications of stereochemistry; reagents and reactions, with mechanisms, used in contemporary organic synthesis; examples taken from the current literature.

453 Advanced Organic Chemistry-Synthesis (4) Strategies and tactics for the synthesis of complex organic molecules. Prereq: CH 452/552.

461 Biochemistry (4) Structure and function of macromolecules. Prereq: CH 336. Exposure to calculus and physical chemistry recommended.

462 Biochemistry (4) Metabolism and metabolic control processes. Energy and sensory transduction mechanisms. Prereq: CH 461/561. Students cannot receive credit for both CH 360 and 462.

463 Biochemistry (4) Mechanisms and regulation of nucleic acid and protein biosynthesis. Other current topics in biochemical genetics. Prereq: CH 462/562 or CH 336 and BI 253.

465 Physical Biochemistry (4) Physical chemical properties of biological macromolecules; forces and interactions to establish and maintain macromolecular conformations; physical bases of spectroscopic, hydrodynamic, and rapid-reaction investigative techniques. Prereq: MATH 253, CH 461. Offered alternate years.

464 RNA Biochemistry (4) Introduction to the diverse field of RNA biochemistry. Prereq: CH 463 or BI 320.


467 Biochemistry Laboratory (4) Methods of modern molecular biology and protein purification.

470 Research Instruments (1-3R) Advanced experimental and theoretical concepts and the operation of instrumentation used in chemical research. Topics include Fourier transform nuclear magnetic resonance (FT-NMR), Fourier transform infrared spectroscopy (FT-IR), electron pair magnetic resonance (EPR), and computers.